HFIP를 용매로 이용하여 나이트론을 만드는 옥사지리딘의 재배열 반응 개발

Abstract

We developed a reaction to generate nitrones from oxaziridines using 1,1,1,3,3,3-hexafluoroisopropyl alcohol (HFIP) that possesses unique chemical properties. In this reaction, we developed the rearrangement of oxaziridines to nitrones at room temperature under mild conditions without any addtitives with various functional group tolarence in good yields.