간 이식 수혜자에서 발견되는 비장동맥류의 임상적 특징 및 예후

Abstract

Background. PHTN is a known risk factor for SAA development and rupture. This study aimed to identify LT recipients who incidentally have SAA and PHTN, and analyze their clinical characteristics and treatment outcomes. Methods. We conducted a retrospective review of LT recipients at our institution from January 2016 to December 2020. Patients with concurrent SAA were identified using 4-phase dynamic CT angiography. We collected data on SAA characteristics, SAA treatment methods, patient demographics, and liver disease-related features. We assessed changes in SAA size through the most recent CT scans performed at least 6 months after the SAA treatment. Results. Of 2,127 LT recipients, 104 patients had incidental SAA, with a prevalence rate of 4.8%. The final analysis included 97 patients with 142 SAA occurrences. In our study, SAAs were predominantly located near the hilum and the distal third portion. Most SAAs were of the saccular type with an average diameter of 1.82 cm. An analysis of the patients divided by SAA diameter showed that those with larger SAA sizes had a higher prevalence of hypertension (p=0.013) and a longer duration of liver disease (p=0.005). The average follow-up period was 52.4 months, and only one patient experienced SAA-related complications. Conclusions. Our results show that SAA accompanied by PHTN mainly exhibits the characteristics of saccular types located distally and at the hilum. Hypertension and the duration of liver diseases were associated with an SAA size. Keywords: Splenic artery aneurysm; Portal hypertension; Liver transplantation recipients