임상화학 분야 정량검사 결과의 단위 및 자릿수 보고 국내현황 고찰

Abstract

Background: The units and unit sizes of quantitative test results vary between laboratories and have not yet been standardized or harmonized in most cases. This study aimed to investigate the current status of units and unit sizes of clinical chemistry in Korea and propose standardized ones.

Methods: The Korean Association of External Quality Assessment Service and College of American Pathologists survey data and textbooks (Tietz 6th ed. and Henry 24th ed.) were reviewed. Members of the Korean Society of Clinical Chemistry were surveyed on 99 items using an online survey platform, and a total of 99 institutions responded. For some items, simulations were conducted for standardized unit size proposals.

Results: The units were consistent in all four references for a total of 54 items (54.5%), whereas, the unit sizes were consistent for 28 items (28.3%). In the questionnaire, 93 items (93.9%) accounted for more than 80% of institutions utilizing the most frequently used unit but only 30 items (30.3%) for unit sizes. As a result of the simulation for the number of digits proposal, it was found that the number of digits currently in use was acceptable for all three participating laboratories.

Conclusions: To the best of our knowledge, this is the first study to investigate the current situation and simulation of the units and unit sizes in clinical chemistry in Korea through a literature review. These data are expected to be used as a basis for the setting of units and unit sizes for reporting quantitative test results in the future.