KLI

Percutaneous Coronary Intervention for Left Main Coronary Artery Disease: Present Status and Future Perspectives

Metadata Downloads
Abstract
For several decades, coronary artery bypass grafting has been regarded as the standard choice of revascularization for significant left main coronary artery (LMCA) disease. However, in conjunction with remarkable advancement of device technology and adjunctive pharmacology, percutaneous coronary intervention (PCI) offers a more expeditious approach with rapid recovery and is a safe and effective alternative in appropriately selected patients with LMCA disease. Several landmark randomized clinical trials showed that PCI with drug-eluting stents for LMCA disease is a safe option with similar long-term survival rates to coronary artery bypass grafting surgery, especially in those with low and intermediate anatomic risk. Although it is expected that the updated evidence from recent randomized clinical trials will determine the next guidelines for the foreseeable future, there are still unresolved and unmet issues of LMCA revascularization and PCI strategy. This paper provides a comprehensive review on the evolution and an update on the management of LMCA disease.
Author(s)
Sangwoo ParkSeung-Jung ParkDuk-Woo Park
Issued Date
2022
Type
Article
Keyword
BMSbare-metal stent(s)CABGcoronary artery bypass graftingCADcoronary artery diseaseDAPTdual antiplatelet therapyDESdrug-eluting stent(s)DKdouble-kissingFFRfractional flow reserveIVUSintravascular ultrasoundLADleft anterior descending arteryLCXleft circumflex arteryLMCAleft main coronary arteryLVEFleft ventricular ejection fractionMACCEmajor adverse cardiac or cerebrovascular eventsMImyocardial infarctionMLAminimal lumen areaPCIpercutaneous coronary interventionRCTrandomized clinical trialiFRinstantaneous wave-free ratioleft main coronary artery disease
DOI
10.1016/j.jacasi.2021.12.011
URI
https://oak.ulsan.ac.kr/handle/2021.oak/15736
Publisher
JACC: Asia
Language
영어
ISSN
2772-3747
Citation Volume
2(2)
Citation Start Page
119
Citation End Page
138
Appears in Collections:
Medicine > Nursing
공개 및 라이선스
  • 공개 구분공개
파일 목록
  • 관련 파일이 존재하지 않습니다.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.