난소종양에서 초음파를 이용한 형태지수에 관한 예비적 연구

Abstract

To evaluate the usefulness of morphology index using ultrasonography for differentiating benign from malignant ovarian tumors, 36 patients with ovarian tumors were examined from March, 1993 to June, 1993. Thirty patients were premenopausal and 6 patients were postmenopausal. Transabdominal sonographic pelvic images of 36 patients were correlated with histopathology. Of 38 ovaries, 31 had benign tumors (6 mucinous cystadenoma, 7 endometrial cyst, 7 mature cystic teratoma, 3 corpus luteal cyst, 1 parovarian cyst, 1 fibroma, 1 simple cyst) and 7 had malignant tumors.

Mean morphology index(MMI±SE) of malignant ovarian tumors, 9.42±0.97 was significantly higher than that of benign ovarian tumors, 4.51±0.36 (P<0.0001).

In premenopausal patients, mean morphology index(MMI±SE) of benign and malignant ovarian tumors was 4.44±0.37, and 9.33±1.45, respectively. In postmenopausal patients, the MMI was 5.5±1.5 for benign ovarian tumors and 9.5±1.5 for malignant tumors. In both premenopausal and premenopausal women, there were no ovarian malignancies in tumors with morphology index below 6.

This scoring system was useful in distinguishing benign from malignant tumors(specificity 74% and sensitivity 100%). Our result is more sensitive but somewhat less specific than the others. The main source of false positive results were mucinous cystadenoma and mature cystic teratoma, because of large tumor volume and solid 멗. This study is going on with combined use of color Doppler and tumor markers and the further results will be presented.

To evaluate the usefulness of morphology index using ultrasonography for differentiating benign from malignant ovarian tumors, 36 patients with ovarian tumors were examined from March, 1993 to June, 1993. Thirty patients were premenopausal and 6 patients were postmenopausal. Transabdominal sonographic pelvic images of 36 patients were correlated with histopathology. Of 38 ovaries, 31 had benign tumors (6 mucinous cystadenoma, 7 endometrial cyst, 7 mature cystic teratoma, 3 corpus luteal cyst, 1 parovarian cyst, 1 fibroma, 1 simple cyst) and 7 had malignant tumors.

Mean morphology index(MMI±SE) of malignant ovarian tumors, 9.42±0.97 was significantly higher than that of benign ovarian tumors, 4.51±0.36 (P<0.0001).

In premenopausal patients, mean morphology index(MMI±SE) of benign and malignant ovarian tumors was 4.44±0.37, and 9.33±1.45, respectively. In postmenopausal patients, the MMI was 5.5±1.5 for benign ovarian tumors and 9.5±1.5 for malignant tumors. In both premenopausal and premenopausal women, there were no ovarian malignancies in tumors with morphology index below 6.

This scoring system was useful in distinguishing benign from malignant tumors(specificity 74% and sensitivity 100%). Our result is more sensitive but somewhat less specific than the others. The main source of false positive results were mucinous cystadenoma and mature cystic teratoma, because of large tumor volume and solid 멗. This study is going on with combined use of color Doppler and tumor markers and the further results will be presented.