신생아 및 영유아에서 설사와 동반된 일과성 메트헤모글로빈혈증의 임상적 고찰

Abstract

Metoemoglobinemia is an uncommon clinical problem generally caused by inherited disorders of hemoglobin or environmental toxicities from oxidizing agents. We experienced 4 neonate and a infant who exhibit transient methemoglobinemia with diarrhea. So we report our experience with 5 unrelated newborns, ranging from 7 to 40 days, who presented with diarrhea, dehydration, acidosis, and transient methemoglobinemia.

No history of toxin exposure and family could be elicited. All were moderately to severely dehydrated, methemoglobin levels ranged from 7.2 to 18.9%. 2 patient showed acidosis and no patient showed decreased arterial oxygen saturation. All patients recovered. One patient was treated by methylene blue and the others were treated by supportive care.

The clinician should be aware of methemoglobinemia with diarrhea to avoid unnecessary work up and management.

Metoemoglobinemia is an uncommon clinical problem generally caused by inherited disorders of hemoglobin or environmental toxicities from oxidizing agents. We experienced 4 neonate and a infant who exhibit transient methemoglobinemia with diarrhea. So we report our experience with 5 unrelated newborns, ranging from 7 to 40 days, who presented with diarrhea, dehydration, acidosis, and transient methemoglobinemia.

No history of toxin exposure and family could be elicited. All were moderately to severely dehydrated, methemoglobin levels ranged from 7.2 to 18.9%. 2 patient showed acidosis and no patient showed decreased arterial oxygen saturation. All patients recovered. One patient was treated by methylene blue and the others were treated by supportive care.

The clinician should be aware of methemoglobinemia with diarrhea to avoid unnecessary work up and management.