전염성 연속종의 임상적 고찰 및 지연형 피부면역반응 검사소견에 관한 연구

Abstract

Molluscum contagiosum is a benign infectious acanthoma caused by molluscum contagiosum virus which has structural features intermediate between the orthopoxvirus group, e.g. vaccinia, and the parapoxvirus group, e.g. orf. There are few reports on the clinical and immunological features of molluscum contagiosum in Korea. This study was aimed to investigate the clinical manifestations of 207 molluscum patients and to evaluate the delayed cutaneous hypersensitivity responsiveness by the Multitest CMI kit(Pasteur Merieux) of 158 molluscum patients and 19 healthy persons as control.

The results were summarized as follows :

1. The relative frequency of molluscum contagiosum on the hospital base in 1989-1992 was 1.1% and molluscum patients visited more frequently in winter and spring than summer and autumn.

2. Among 207 patients, 97(46.7%) were males and 110(53.1%) were female. The peak age of incidence was between 6-10 years of age and 83.6% were under 10 years of age.

3. The mean duration of skin lesion was 4.5 months and back was the most common in volved site(65.7%).

4. Atopic dermatitis(29%) was the most common combined skin disease and 43.9% of the patients had itching sensation.

5. The intensity of reaction(IR) and rate of reaction(RR) in molluscum patients were not significantly reduced than in controls.

Molluscum contagiosum is a benign infectious acanthoma caused by molluscum contagiosum virus which has structural features intermediate between the orthopoxvirus group, e.g. vaccinia, and the parapoxvirus group, e.g. orf. There are few reports on the clinical and immunological features of molluscum contagiosum in Korea. This study was aimed to investigate the clinical manifestations of 207 molluscum patients and to evaluate the delayed cutaneous hypersensitivity responsiveness by the Multitest CMI kit(Pasteur Merieux) of 158 molluscum patients and 19 healthy persons as control.

The results were summarized as follows :

1. The relative frequency of molluscum contagiosum on the hospital base in 1989-1992 was 1.1% and molluscum patients visited more frequently in winter and spring than summer and autumn.

2. Among 207 patients, 97(46.7%) were males and 110(53.1%) were female. The peak age of incidence was between 6-10 years of age and 83.6% were under 10 years of age.

3. The mean duration of skin lesion was 4.5 months and back was the most common in volved site(65.7%).

4. Atopic dermatitis(29%) was the most common combined skin disease and 43.9% of the patients had itching sensation.

5. The intensity of reaction(IR) and rate of reaction(RR) in molluscum patients were not significantly reduced than in controls.