황을 포함하는 새로운 온도 감응성 폴리 아크릴아마이드의 합성

Abstract

Thermoresponsive polyacrylamides substituted with sulfide, sulfone or sulfoxide was successfully prepared. The solubility of sulfur-containing polyacrylamides in water can be easily controlled by changing the number of oxygen atoms in sulfur atom or the chain length of the end of polyacrylamide. Moreover, an N-(2-(ethylsulfonyl)ethyl)- acrylamide (P1SO2) was polymerized from poly[N-(2-(propylthio)ethyl)acrylamide (P2S) macroCTA via reversible addition-fragmentation chain transfer (RAFT) polymerization, resulting in the formation of a well-defined block copolymer of P2S-b-P1SO2. The resulting block copolymer, P2S-b-P1SO2, was assembled in water to yield micelles that consist of a P1SO2 block forming a hydrophilic shell and a P2S block forming a hydrophobic core. P2S block was ultimately synthesized via post-polymerization modification using H2O2, which caused the conversion of the sulfide of P2S to sulfoxide that is hydrophilic in water, leading to the transformation of micelles to unmers.