간의 국소 결절 과형성의 수술의 적응증; 48예의 단일 기관 연구

Abstract

Background : Focal nodular hyperplasia (FNH) is one of the most common benign tumors of the liver. There is still lack of evidence on surgical indication of FNH. This study intended to analyze the surgical indications of FNH. Methods : We analyzed the 48 cases of FNH diagnosed after hepatic resection Results : The common reasons leading to surgical resection were diagnostic uncertainty (n = 31) and persistent symptoms (n = 8). Percutaneous biopsy was performed in 14 patients and diagnosed as FNH in 9, hepatic adenoma in 1, hepatocellular carcinoma in 1, plasmacytoma in 1, angiosarcoma in 1, and atypical hepatocellular proliferation in 1. Minor hepatectomy (n = 37) was performed more frequently than major hepatectomy (n = 11). Open hepatectomy (n = 29) was performed more frequently than laparoscopic hepatectomy (n = 19), but laparoscopic and minimally invasive surgery was frequently performed during the late phase of the study period. Postoperative surgical complications occurred in two patients (4.1%). Conclusion : FNH can be diagnosed by imaging studies, but surgical treatment can be considered if there is diagnostic uncertainty or persistent symptoms.