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복부 대동맥류의 혈관 내 치료 후의 동맥류 낭의 크기 감소에 관련된 새로운 예측 인자

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Abstract
Background: The aims of this study were to identify new predictors of sac behavior after endovascular aortic aneurysm repair (EVAR) and to investigate whether the sac behavior is associated with long-term clinical outcomes.
Methods and Results: A total of 168 patients undergoing successful EVAR for abdominal aortic aneurysms with computed tomography angiography (CTA) follow-up of at least 1 year were included. Predictors of aneurysm sac behavior and its impact on long-term clinical outcomes were retrospectively analyzed. According to the sac behavior, eligible patients were stratified into the sac regression group (n=79, 47.0%) and the sac expansion group (n=89, 53.0%). Patients in the sac regression group were younger (P=0.036) and more likely to take sarpogrelate hydrochloride at follow-up (P=0.011) than those in the sac expansion group. The incidence of postimplantation syndrome (PIS) was significantly higher in the sac regression group (P=0.005). On multivariate analysis, sac regression was more likely to occur in those with PIS (hazard ratio [HR], 1.68; 95% confidence interval [CI], 1.07–2.64; P=0.023) and less likely to occur in those with transient type II endoleaks (HR, 0.43; 95% CI, 0.20–0.95; P=0.037) and higher thrombus density within the sac on follow-up CTA (HR, 0.97; 95% CI, 0.95–0.99; P=0.013). Sac expansion was associated with significantly higher rates of reintervention during the follow-up period (P=0.001).
Conclusions: In addition to type II endoleaks, PIS and thrombus density are new predictors of aneurysm sac behavior, and sac regression is significantly associated with lower rates of reintervention.
Author(s)
정민재
Issued Date
2018
Awarded Date
2019-02
Type
Dissertation
Keyword
Aortic AneurysmAbdominalEndovascular ProceduresTreatment Outcome
URI
https://oak.ulsan.ac.kr/handle/2021.oak/6748
http://ulsan.dcollection.net/common/orgView/200000173633
Alternative Author(s)
Min-Jae Jeong
Affiliation
울산대학교
Department
일반대학원 의학과
Advisor
조용필
Degree
Doctor
Publisher
울산대학교 일반대학원 의학과
Language
eng
Rights
울산대학교 논문은 저작권에 의해 보호받습니다.
Appears in Collections:
Medicine > 2. Theses (Ph.D)
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