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Respiratory symptoms and health-related quality of life in post-tuberculosis subjects with physician-diagnosed bronchiectasis: a cross-sectional study

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Abstract
Background: Prevalence, respiratory symptoms, and quality of life (QoL) in post-tuberculosis (TB) subjects with bronchiectasis are not well elucidated. Methods: Subjects who participated in the Korea National Health and Nutritional Examination Survey 2007-2009 were enrolled in this cross-sectional study. We evaluated the prevalence of physician-diagnosed bronchiectasis among post-TB subjects. We compared respiratory symptoms, physical activity limitations, and QoL between post-TB subjects with and without bronchiectasis. Results: The prevalence of bronchiectasis was 3.3% among 963 post-TB subjects. Post-TB subjects with bronchiectasis showed a higher rate of asthma (29.6% vs. 4.9%, P<0.001) than those without bronchiectasis. Post-TB subjects with bronchiectasis showed more cough (23.9% vs. 6.7%, P=0.033) and physical activity limitations due to respiratory diseases (35.0% vs. 8.9%, P=0.033) than those without bronchiectasis. Furthermore, compared with post-TB subjects without bronchiectasis, those with bronchiectasis had lower QoL measured by the EuroQoL five-dimension (EQ-5D) index (0.84 vs. 0.93, P=0.048). Linear regression analysis found that the EQ-5D index in post-TB subjects with bronchiectasis was significantly lower than in those without bronchiectasis (difference estimate =-0.089, P=0.030), especially in the anxiety/depression component. Conclusions: Post-TB subjects with bronchiectasis had more cough and physical activity limitations and lower health-related QoL than those without bronchiectasis.
Author(s)
나승원오연목Bumhee YangHayoung ChoiHo Joo YoonHye Yun ParkHyo Jun JangHyo Jun JangHyun LeeJang Won SohnSang-Heon KimSeung-Jin YooTaehee KimYong-Soo KwonYun Su Sim
Issued Date
2021
Type
Article
Keyword
Korea NHANESTuberculosis (TB)bronchiectasisquality of life (QoL)
DOI
10.21037/jtd-20-3028
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7161
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2573434218&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Respiratory%20symptoms%20and%20health-related%20quality%20of%20life%20in%20post-tuberculosis%20subjects%20with%20physician-diagnosed%20bronchiectasis:%20a%20cross-sectional%20study&amp;offset=0&amp;pcAvailability=true
Publisher
JOURNAL OF THORACIC DISEASE
Location
홍콩
Language
영어
ISSN
2072-1439
Citation Volume
13
Citation Number
8
Citation Start Page
4894
Citation End Page
4902
Appears in Collections:
Medicine > Medicine
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