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Clinical Characteristics of Patients with Post-Tuberculosis Bronchiectasis: Findings from the KMBARC Registry

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Abstract
The clinical characteristics of patients with post-tuberculosis (TB) bronchiectasis have not been well evaluated. We enrolled 598 patients with bronchiectasis who participated in the Korean prospective bronchiectasis registry and compared the characteristics of post-TB bronchiectasis (19.7%) with post-infectious (19.6%), idiopathic (40.8%), and other (19.9%) bronchiectasis. The patients with post-TB bronchiectasis had a lower body mass index, higher rate of chronic obstructive pulmonary disease, and lower rate of asthma than those in the other groups. The patients with post-TB bronchiectasis had more upper lobe involvement, more severe radiological extent, and worse lung function than those in the other groups. Long-acting muscarinic antagonist/long-acting ß agonist use and mucolytics were more commonly used in the patients with post-TB bronchiectasis than those in the other groups, while inhaled corticosteroid/long-acting ß agonist was less commonly used. There were no significant intergroup differences in bronchiectasis severity scores except for FACED, the number of exacerbations, and quality of life. Post-TB bronchiectasis is characterised by reduced lung function and higher rates of mucolytic use when compared with other bronchiectasis; thus, adequate bronchodilator use and airway clearance techniques may alleviate symptom burden in this population.

Keywords: bronchiectasis; treatment; tuberculosis.
Author(s)
나승원오연목이재승Hayoung ChoiHyun Kuk KimHyun LeeOn Behalf Of The KmbarcSang-Heon KimSoo-Jung UmYong-Soo Kwon
Issued Date
2021
Type
Article
Keyword
AsthmabronchiectasisChronic obstructive pulmonary diseaseCystic fibrosisDyspneaEtiologyLaboratoriesPatientsQuality of lifeQuestionnairesRheumatoid arthritistreatmentTuberculosis
DOI
10.3390/jcm10194542
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7182
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_98b3d86b3b6645fb97526b09f0e240c8&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Clinical%20Characteristics%20of%20Patients%20with%20Post-Tuberculosis%20Bronchiectasis:%20Findings%20from%20the%20KMBARC%20Registry&offset=0&pcAvailability=true
Publisher
Journal of clinical medicine
Location
스위스
Language
영어
ISSN
2077-0383
Citation Volume
10
Citation Number
19
Citation Start Page
4542
Citation End Page
4542
Appears in Collections:
Medicine > Medicine
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