KLI

Prognostic Value of Computed Tomographic Coronary Angiography for Long-Term Major Adverse Cardiac Events after Liver Transplantation

Metadata Downloads
Abstract
Computed tomographic coronary angiography (CTCA) has prognostic value for early major adverse cardiac events (MACEs) after liver transplantation. However, the association between CTCA and long-term MACEs in liver transplant (LT) recipients remains unknown. We evaluated the association between CTCA and long-term MACEs within 5 years after living donor liver transplantation (LDLT). A total of 628 LDLT recipients who underwent CTCA were analyzed between 2010 and 2012. MACEs were investigated within 5 years after LDLT. The factors associated with long-term MACEs in transplant recipients were evaluated. Only 48 (7.6%) patients developed MACEs. In the Fine and Gray competing risk regression, a coronary artery calcium score (CACS) of >400 combined with obstructive coronary artery disease (CAD) (subdistribution hazard ratio: 5.01, 95% confidence interval: 2.37-10.58, p < 0.001), age (1.05, 1.01-1.10, p = 0.018), diabetes mellitus (2.43, 1.37-4.29, p = 0.002), dyslipidemia (2.45, 1.23-4.70, p = 0.023), and creatinine (1.19, 1.08-1.30, p < 0.001) were independently associated with long-term MACEs. CACS (>400) combined with obstructive CAD may be associated with MACEs within 5 years after LDLT, suggesting the importance of preoperative noninvasive CTCA in LT recipients. The evaluation of coronary artery stenosis on CTCA combined with CACS may have a prognostic value for long-term MACEs in LT recipients.
Author(s)
강준원구현정김두환김영국김우일양동현이승규하태용황신
Issued Date
2021
Type
Article
Keyword
cardiovascular disease&nbsp;computed tomographic angiography&nbsp;coronary artery calcium score&nbsp;coronary vessels&nbsp;liver transplantations
DOI
10.3390/jcm10143132
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7295
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_aa11e563909b44ca9645eabcab784bd2&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Prognostic%20Value%20of%20Computed%20Tomographic%20Coronary%20Angiography%20for%20Long-Term%20Major%20Adverse%20Cardiac%20Events%20after%20Liver%20Transplantation&amp;offset=0&amp;pcAvailability=true
Publisher
JOURNAL OF CLINICAL MEDICINE
Location
스위스
Language
영어
ISSN
2077-0383
Citation Volume
10
Citation Number
14
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.