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US LI-RADS visualization score: diagnostic outcome of ultrasound-guided focal hepatic lesion biopsy in patients at risk for hepatocellular carcinoma

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Abstract
Purpose: This study investigated the diagnostic outcome of ultrasound (US)-guided focal hepatic lesion biopsy in patients at risk for hepatocellular carcinoma (HCC) and evaluated the US visualization score as a risk factor for non-diagnostic results.

Methods: We retrospectively evaluated 208 focal hepatic lesions in 208 patients who underwent US- guided biopsy in 2016. Using the US Liver Imaging Reporting and Data System version 2017, each exam was assigned a US visualization score (A, B, or C). Final diagnoses were made using pathology reports, and biopsy results were categorized as diagnostic or non-diagnostic. Univariable and multivariable analyses were performed to determine risk factors for non-diagnostic results, including US visualization score and other clinical covariates.

Results: Of the 208 lesions, 85.1% were diagnostic and 14.9% were non-diagnostic. The rates of non-diagnostic results were 8.9%, 25.5%, and 57.1% for scores of A, B, and C, respectively. In the univariable analysis, scores of B or C were associated with a significantly higher rate of nondiagnostic results than scores of A (58.1% vs. 24.9%, P<0.001). In the multivariable analysis, US visualization score of B or C (adjusted odds ratio [aOR], 2.7; P=0.027), high-risk needle pathway usage (aOR, 5.7; P=0.001), and lesion size <= 2.0 cm (aOR, 2.7; P=0.024) were independent risk factors for non-diagnostic results.

Conclusion: US-guided biopsy had a high diagnostic yield for focal hepatic lesions in patients at risk for HCC. US visualization score of B or C, lesion size =2.0 cm, and high-risk needle pathway usage were independent risk factors for non-diagnostic results.
Author(s)
강지훈최상현김소연이소정신용문원형진김표년
Issued Date
2021
Type
Article
Keyword
LiverHepatocellular carcinomaUltrasonographyBiopsyDiagnosis
DOI
10.14366/usg.19066
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7327
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_9637715&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,US%20LI-RADS%20visualization%20score:%20diagnostic%20outcome%20of%20ultrasound-guided%20focal%20hepatic%20lesion%20biopsy%20in%20patients%20at%20risk%20for%20hepatocellular%20carcinoma&amp;offset=0&amp;pcAvailability=true
Publisher
ULTRASONOGRAPHY
Location
대한민국
Language
영어
ISSN
2288-5919
Citation Volume
40
Citation Number
1
Citation Start Page
167
Citation End Page
175
Appears in Collections:
Medicine > Medicine
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