US LI-RADS visualization score: diagnostic outcome of ultrasound-guided focal hepatic lesion biopsy in patients at risk for hepatocellular carcinoma
- Abstract
- Purpose: This study investigated the diagnostic outcome of ultrasound (US)-guided focal hepatic lesion biopsy in patients at risk for hepatocellular carcinoma (HCC) and evaluated the US visualization score as a risk factor for non-diagnostic results.
Methods: We retrospectively evaluated 208 focal hepatic lesions in 208 patients who underwent US- guided biopsy in 2016. Using the US Liver Imaging Reporting and Data System version 2017, each exam was assigned a US visualization score (A, B, or C). Final diagnoses were made using pathology reports, and biopsy results were categorized as diagnostic or non-diagnostic. Univariable and multivariable analyses were performed to determine risk factors for non-diagnostic results, including US visualization score and other clinical covariates.
Results: Of the 208 lesions, 85.1% were diagnostic and 14.9% were non-diagnostic. The rates of non-diagnostic results were 8.9%, 25.5%, and 57.1% for scores of A, B, and C, respectively. In the univariable analysis, scores of B or C were associated with a significantly higher rate of nondiagnostic results than scores of A (58.1% vs. 24.9%, P<0.001). In the multivariable analysis, US visualization score of B or C (adjusted odds ratio [aOR], 2.7; P=0.027), high-risk needle pathway usage (aOR, 5.7; P=0.001), and lesion size <= 2.0 cm (aOR, 2.7; P=0.024) were independent risk factors for non-diagnostic results.
Conclusion: US-guided biopsy had a high diagnostic yield for focal hepatic lesions in patients at risk for HCC. US visualization score of B or C, lesion size =2.0 cm, and high-risk needle pathway usage were independent risk factors for non-diagnostic results.
- Author(s)
- 강지훈; 최상현; 김소연; 이소정; 신용문; 원형진; 김표년
- Issued Date
- 2021
- Type
- Article
- Keyword
- Liver; Hepatocellular carcinoma; Ultrasonography; Biopsy; Diagnosis
- DOI
- 10.14366/usg.19066
- URI
- https://oak.ulsan.ac.kr/handle/2021.oak/7327
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_9637715&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,US%20LI-RADS%20visualization%20score:%20diagnostic%20outcome%20of%20ultrasound-guided%20focal%20hepatic%20lesion%20biopsy%20in%20patients%20at%20risk%20for%20hepatocellular%20carcinoma&offset=0&pcAvailability=true
- Publisher
- ULTRASONOGRAPHY
- Location
- 대한민국
- Language
- 영어
- ISSN
- 2288-5919
- Citation Volume
- 40
- Citation Number
- 1
- Citation Start Page
- 167
- Citation End Page
- 175
-
Appears in Collections:
- Medicine > Medicine
- Authorize & License
-
- Files in This Item:
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.