KLI

Breast-conserving surgery with 3D-printed surgical guide: a single-center, prospective clinical study

Metadata Downloads
Abstract
To facilitate precise tumor resection at the time of breast-conserving surgery (BCS), we developed and implemented a magnetic resonance imaging (MRI)-based three-dimensional-printed (3DP) breast surgical guide (BSG). This prospective cohort study was conducted at a single institution from July 2017 to February 2019 on women with breast cancer who underwent partial breast resection using patient-specific 3DP BSGs. Eighty-eight patients with invasive cancer were enrolled, of whom 1 patient had bilateral breast cancer. The mean size of the tumor long-axis on MRI before surgery was 2.80.9 cm, and multiple tumors were observed in 34 patients. In 16 cases (18.0%), the resection margin was tumor-positive according to intraoperative frozen biopsy; all of these tumors were ductal carcinoma in situ and were re-excised intraoperatively. In 93.3% of the cases, the resection margin was tumor-free in the permanent pathology. The mean pathological tumor size was 1.7 +/- 1.0 cm, and the mean distance from the tumor to the border was 1.5 +/- 1.0 cm. This exploratory study showed that the tumor area on the MRI could be directly displayed on the breast when using a 3DP BSG for BCS, thereby allowing precise surgery and safe tumor removal.Trial Registration Clinical Research Information Service (CRIS) Identifier (No. KCT0002375, KCT0003043).
Author(s)
고범석공경엽김남국김지선김학희김희정서준범손병호안세현이새별이종원정일용정재호Zhen-Yu Wu
Issued Date
2021
Type
Article
Keyword
BiopsyBreast cancerInvasivenessMagnetic resonance imagingMastectomyPatientsSurgerySurgical oncologyTumors
DOI
10.1038/s41598-021-81936-8
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7344
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_3929c0ae2e0e4fd8a5b2f6f1ac4c8886&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Breast-conserving%20surgery%20with%203D-printed%20surgical%20guide:%20a%20single-center,%20prospective%20clinical%20study&offset=0&pcAvailability=true
Publisher
SCIENTIFIC REPORTS
Location
영국
Language
영어
ISSN
2045-2322
Citation Volume
11
Citation Number
1
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.