KLI

Inadequate Ultrasound Examination in Hepatocellular Carcinoma Surveillance: A Systematic Review and Meta-Analysis

Metadata Downloads
Abstract
We aimed to systematically evaluate the incidence of inadequate US in hepatocellular carcinoma (HCC) surveillance and determine the risk factors. Original studies reporting the incidence or risk factors for inadequate US were identified in MEDLINE, EMBASE, and the Cochrane database. The pooled incidence of inadequate US was calculated using a random effects model, and subgroup analyses were performed. The pooled odds ratio (OR) was calculated for each risk factor for inadequate US. Six eligible articles were identified from 756 screened articles (4250 patients). The pooled incidence of inadequate US was 21.5%. Significantly higher rates of inadequate US were noted in studies including patients with and without hepatic observations compared with those evaluating only patients with hepatic observations (23.2% vs. 18.8%), studies using US alone compared with US plus alpha-fetoprotein (28.0% vs. 20.8%), and those using pathology and imaging as a reference standard compared with imaging only (23.2% vs. 17.9%). Nonalcoholic steatohepatitis (OR = 2.3 (1.07-4.84)), Child-Pugh B cirrhosis (OR = 2.2 (1.10-4.37)), and high body mass index (OR = 2.2 (1.12-4.24)) were significant risk factors for inadequate US (p <= 0.04). In patients at risk of HCC, 21.5% of US surveillance was inadequate. An alternative surveillance modality might be considered in patients with risk factors.
Author(s)
홍승백김동환최상현김소연이지성이남경최준일
Issued Date
2021
Type
Article
Keyword
Biasbody mass indexhepatocellular carcinomaLiver cancerLiver diseasesMagnetic resonance imagingMedical prognosisnonalcoholic steatohepatitisPatientsRisk factorsSurveillancesystematic reviewUltrasonic imagingultrasound
DOI
10.3390/jcm10163535
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7394
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_a0f5254fecf24bcf87597791ef23d56e&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Inadequate%20Ultrasound%20Examination%20in%20Hepatocellular%20Carcinoma%20Surveillance:%20A%20Systematic%20Review%20and%20Meta-Analysis&amp;offset=0&amp;pcAvailability=true
Publisher
JOURNAL OF CLINICAL MEDICINE
Location
스위스
Language
한국어
ISSN
2077-0383
Citation Volume
10
Citation Number
16
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
공개 및 라이선스
  • 공개 구분공개
파일 목록
  • 관련 파일이 존재하지 않습니다.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.