KLI

Inter-reader reliability of contrast-enhanced ultrasound Liver Imaging Reporting and Data System: a meta-analysis

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Abstract
Purpose To systematically determine the inter-reader reliability of the contrast-enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI-RADS), with emphasis on its major features for hepatocellular carcinoma (HCC) and LR-M (LI-RADS category M) features for non-HCC malignancy.

Methods MEDLINE, EMBASE, and Cochrane databases were searched from January 2016 to March 2021 to identify original articles reporting the inter-reader reliability of CEUS LI-RADS. Meta-analytic pooled kappa values (kappa) were calculated for major features [nonrim arterial-phase hyperenhancement (APHE), mild and late washout], LR-M features (rim APHE, early washout), and LI-RADS categorization using the DerSimonian-Laird random-effects model. Meta-regression analysis was performed to explore any causes of study heterogeneity.

Results Twelve studies with a total of 2862 lesions were included. The meta-analytic pooled kappa of nonrim APHE, mild and late washout, rim APHE, early washout, and LI-RADS categorization were 0.73 [95% confidence interval (CI), 0.67 - 0.79], 0.69 (95% CI, 0.54-0.84), 0.54 (95% CI, 0.37-0.71), 0.62 (95% CI, 0.45-0.79), and 0.75 (95% CI, 0.64-0.87), respectively. Compared with the major features, LR-M features had a lower meta-analytic pooled kappa. Substantial study heterogeneity was noted in the LI-RADS categorization, and lesion size (p = 0.03) and the homogeneity in reader experience (p = 0.03) were significantly associated with study heterogeneity.

Conclusions CEUS LI-RADS showed substantial inter-reader reliability for major features and LI-RADS categorization, but relatively lower reliability was found for LR-M features. In our opinion, the definitions of imaging features require further refinement to improve the inter-reader reliability of CEUS LI-RADS.

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Author(s)
강지훈최상현이지성김동욱장종건
Issued Date
2021
Type
Article
Keyword
Diagnostic imagingGastroentnerologyHepatologyImagingLiverMedicineMedicine &Public HealthRadiologyUltrasound imaging
DOI
10.1007/s00261-021-03169-7
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7423
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2544162018&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Inter-reader%20reliability%20of%20contrast-enhanced%20ultrasound%20Liver%20Imaging%20Reporting%20and%20Data%20System:%20a%20meta-analysis&offset=0&pcAvailability=true
Publisher
ABDOMINAL RADIOLOGY
Location
미국
Language
한국어
ISSN
2366-004X
Citation Volume
46
Citation Number
10
Citation Start Page
4671
Citation End Page
4681
Appears in Collections:
Medicine > Medicine
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