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Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience

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Abstract
ObjectiveTo report our experience with management of fetuses with congenital high airway obstruction syndrome (CHAOS).
MethodsWe retrospectively reviewed the cases of fetuses who were prenatally diagnosed and postnatally confirmed withCHAOS between 2010 and 2019 at Asan Medical Center, Seoul, Korea.
ResultsOf 13 fetuses prenatally diagnosed with CHAOS, 7 were lost to follow-up and 6 were postnatally confirmed as havingCHAOS. All fetuses, except one were delivered via cesarean section with an ex utero intrapartum treatment (EXIT)procedure. Two patients had coexisting congenital heart diseases requiring several cardiac surgeries following birth.
Both of these patients demonstrated developmental delay; however, the remaining 4 had a normal developmentexcept for expressive language. Two infants died of respiratory complications, and the remaining 4 were alive at theend of the follow-up period. All 4 live patients underwent tracheostomy with planned reconstruction surgery. Threechildren are now able to phonate, and 1 can maintain a conservation.
ConclusionThe proper management of CHAOS using the EXIT procedure results in high survival and low hypoxemia-inducedcomplication rates. Therefore, an accurate prenatal diagnosis is necessary for an appropriate perinatal management.
Author(s)
정상희이미영강옥주김리나정진훈원혜성이필량정의석이병섭최우종이윤세
Issued Date
2021
Type
Article
Keyword
Airway obstructionLaryngeal diseasePrenatal diagnosisTracheostomy
DOI
10.5468/ogs.20266
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7516
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_kiss_primary_3853539&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Perinatal%20outcome%20of%20fetuses%20with%20congenital%20high%20airway%20obstruction%20syndrome:%20a%20single-center%20experience&offset=0&pcAvailability=true
Publisher
Obstetrics & Gynecology Science
Location
대한민국
Language
한국어
ISSN
2287-8580
Citation Volume
64
Citation Number
1
Citation Start Page
52
Citation End Page
61
Appears in Collections:
Medicine > Medicine
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