KLI

Comparison of Clinical and Biomechanical Outcomes of Small Incision Lenticule Extraction With 120- and 140-μm Cap Thickness

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Abstract
Purpose
The purpose of this study was to compare the clinical outcomes and corneal biomechanical changes between 120-μm and 140-μm cap thickness after small incision lenticule extraction (SMILE).
Methods
This prospective study included 150 eyes (150 patients: 91 eyes in the 120-μm group, and 59 eyes in the 140-μm group) who underwent SMILE. Enhanced correction nomograms were applied for patients according to cap thickness. Clinical outcomes, including visual acuity, refraction, and corneal wavefront aberrations, were compared between the two groups. Corneal biomechanics were evaluated using the Corvis ST (Oculus, Wetzlar, Germany).
Results
The mean uncorrected-distance visual acuity, safety and efficacy indices, and refractive predictability were comparable in the 120-μm and 140-μm groups after SMILE. The postoperative total corneal root mean square higher-order aberrations (HOAs) and spherical aberrations was 0.48 ± 0.31 and 0.26 ± 0.10 in the 120-μm group, and 0.53 ± 0.16 and 0.34 ± 0.13 in the 140-μm group, which showed significant differences between the two groups (P = 0.027, and <0.001, respectively). Although corneal stiffness decreased after SMILE in both groups, the changes in the deformation amplitude ratio were significantly higher in the 140-μm group than in the 120-μm group (P = 0.022).
Conclusions
SMILE with 120-μm and 140-μm cap thickness provided excellent predictable outcomes according to our enhanced correction nomogram. The amount of tissue removal required to achieve the same amount of refractive correction was greater in the thicker cap group. The induction of corneal HOAs and weakening of corneal biomechanics were less pronounced in the thin-cap group, which may be associated with the thinner cap, lesser lenticule thickness, or thicker residual stromal bed.
Author(s)
강성용김응권김태임서경률이훈전익현진승기Cynthia J Roberts
Issued Date
2021
Type
Article
Keyword
cap thicknesscorneal biomechanicsSMILEvisual outcome
DOI
10.1167/tvst.10.8.15
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7670
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8288062&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Comparison%20of%20Clinical%20and%20Biomechanical%20Outcomes%20of%20Small%20Incision%20Lenticule%20Extraction%20With%20120-%20and%20140-%CE%BCm%20Cap%20Thickness&amp;offset=0&amp;pcAvailability=true
Publisher
Translational Vision Science & Technology
Location
미국
Language
한국어
ISSN
2164-2591
Citation Volume
10
Citation Number
8
Citation Start Page
15
Citation End Page
15
Appears in Collections:
Medicine > Medicine
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