Tat-aldose reductase prevents dopaminergic neuronal cell death by inhibiting oxidative stress and MAPK activation
- Abstract
- Aldose reductase (AR) is known to detoxify aldehydes and prevent oxidative stress. Although AR exerts antioxidant effects, the role of AR in Parkinson's disease (Pd) remains unclear. The objective of the present study was to investigate the protective effects of AR protein against 1-methyl-4-phenylpyridinium (MPP
- Issued Date
- 2021
- Type
- Article
- Keyword
- Aldehydes; Aldose reductase; Analysis; Antibodies; Apoptosis; Biochemistry; Biotechnology; Cell death; Cloning; Ethylenediaminetetraacetic acid; Health aspects; Investigations; Microscopy; Monosaccharides; Neurons; Oxidative stress; Parkinsons disease; Peptides; Photographic industry; Political activity; Political aspects; Protein kinases; Proteins; Reagents; Scientific equipment and supplies industry; Sugars
- URI
- https://oak.ulsan.ac.kr/handle/2021.oak/7769
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_journals_2477399709&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Tat-aldose%20reductase%20prevents%20dopaminergic%20neuronal%20cell%20death%20by%20inhibiting%20oxidative%20stress%20and%20MAPK%20activation&offset=0&pcAvailability=true
- Publisher
- INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Location
- 영국
- Language
- 영어
- ISSN
- 1107-3756
- Citation Volume
- 47
- Citation Number
- 2
- Citation Start Page
- 751
- Citation End Page
- 760
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