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Tat-aldose reductase prevents dopaminergic neuronal cell death by inhibiting oxidative stress and MAPK activation

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Abstract
Aldose reductase (AR) is known to detoxify aldehydes and prevent oxidative stress. Although AR exerts antioxidant effects, the role of AR in Parkinson's disease (Pd) remains unclear. The objective of the present study was to investigate the protective effects of AR protein against 1-methyl-4-phenylpyridinium (MPP
Author(s)
조수빈음원식신민재여현지여은지최연주권현정조성우박진서한규형이근욱박종국김덕수김대원최수영
Issued Date
2021
Type
Article
Keyword
AldehydesAldose reductaseAnalysisAntibodiesApoptosisBiochemistryBiotechnologyCell deathCloningEthylenediaminetetraacetic acidHealth aspectsInvestigationsMicroscopyMonosaccharidesNeuronsOxidative stressParkinsons diseasePeptidesPhotographic industryPolitical activityPolitical aspectsProtein kinasesProteinsReagentsScientific equipment and supplies industrySugars
DOI
10.3892/ijmm.2020.4812
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7769
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_journals_2477399709&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Tat-aldose%20reductase%20prevents%20dopaminergic%20neuronal%20cell%20death%20by%20inhibiting%20oxidative%20stress%20and%20MAPK%20activation&offset=0&pcAvailability=true
Publisher
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Location
영국
Language
영어
ISSN
1107-3756
Citation Volume
47
Citation Number
2
Citation Start Page
751
Citation End Page
760
Appears in Collections:
Medicine > Medicine
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