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Efficacy of radiofrequency ablation for recurrent thyroid cancer invading the airways

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Abstract
Objectives: To evaluate the efficacy of radiofrequency ablation (RFA) in patients with recurrent thyroid cancer invading the airways. Methods: We reviewed patients who had undergone RFA for recurrent thyroid cancer in the central compartment after total thyroidectomy between January 2008 and December 2018. All tumors were classified according to their association with the laryngeal structure and trachea. The volume reduction rate (VRR) and complete disappearance rate were calculated, and their differences were determined relative to the association between the tumor and trachea. Complication rates associated with RFA were evaluated. Results: The study population included 119 patients with 172 recurrent tumors. Mean VRR was 81.2% ± 55.7%, with 124 tumors (72.1%) completely disappearing after a mean follow-up of 47.9 ± 35.4 months. The complete disappearance rate of recurrent tumors not in contact with the trachea was highest, followed by tumors forming acute angles, right angles, and obtuse angles with the trachea, and tumors with intraluminal tracheal invasion (p value < 0.001). The overall complication rate was 21.4%. Conclusions: RFA is effective and safe for the local control of recurrent tumors in the central neck compartment after total thyroidectomy, even for tumors invading the airways, and may be considered an alternative to surgical resection. The inverse relationship between RFA efficacy and airway invasion suggests that early RFA may benefit patients with recurrent tumors in the central neck compartment. Key Points: ? RFA achieved a mean VRR of 81.2% ± 55.7% and complete disappearance of 124 tumors (72.1%) after a mean follow-up of 47.9 ± 35.4 months. ? The complete disappearance rate of recurrent tumors not in contact with the trachea was the highest, followed by tumors forming acute angles, right angles, and obtuse angles with the trachea, and tumors with intraluminal tracheal invasion. ? Stent-assisted RFA may be a good alternative for palliative treatment of recurrent tumors with intraluminal tracheal invasion.
Author(s)
김태용백정환성태연송동은이정현정새롬최영준
Issued Date
2021
Type
Article
Keyword
Ablation (Surgery)Catheter AblationChronic DiseaseDiagnostic RadiologyDiseasesHumansImagingInternal MedicineInterventionalInterventional RadiologyMedical researchMedicineMedicine &amp; Public HealthExperimentalLocalNeuroradiologyRadiofrequency AblationRadiologyRelapseThyroid cancerThyroid Neoplasms - surgeryThyroidectomyTreatment OutcomeUltrasoundUltrasound imaging
DOI
10.1007/s00330-020-07283-w
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7874
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2444376422&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Efficacy%20of%20radiofrequency%20ablation%20for%20recurrent%20thyroid%20cancer%20invading%20the%20airways&amp;offset=0&amp;pcAvailability=true
Publisher
EUROPEAN RADIOLOGY
Location
오스트리아
Language
영어
ISSN
0938-7994
Citation Volume
31
Citation Number
4
Citation Start Page
2153
Citation End Page
2160
Appears in Collections:
Medicine > Medicine
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