Diagnostic yield of post-bronchoscopy sputum for diagnosing pauci-bacillary pulmonary tuberculosis
- Abstract
- Background: A few studies have mentioned that post-bronchoscopy sputum (PBS) could improve the diagnostic yield in pauci-bacillary pulmonary tuberculosis (PTB). Therefore, we evaluated the diagnostic yield of PBS for diagnosing pauci-bacillaryPTB. Methods: Clinical data of immunocompromised adult patients with pauci-bacillary PTB were retrospectively retrieved at a tertiary hospital in Seoul, South Korea over a 5-year period. We analyzed patients who underwent bronchoscopy examinations for diagnosing pauci-bacillary PTB. Results: Ninety patients were finally analyzed. Of these patients, 76 patients were tested with PBS. Six (8%) of these patients had positive results on AFB smear of PBS alone. Additionally, 52 patients (68%) had positive results on mycobacterial culture and 12 (16%) had positive results on mycobacterial culture of PBS exclusively. Therefore, in this study population, a total of 18 patients (20%) were finally diagnosed as having PTB with PBS results only, even though AFB smear microscopy and culture of other specimens had negative results. Conclusions: PBS could improve the diagnostic yield by 20% when diagnosing pauci-bacillary PTB. In addition, about 8% of the patients could be diagnosed rapidly because of AFB smear microscopy positivity for PBS. Therefore, PBS use should be considered as a complementary diagnostic approach in patients with suspected pauci-bacillary PTB.
- Author(s)
- 김성한; 박정하; 심태선; 조경욱
- Issued Date
- 2021
- Type
- Article
- Keyword
- Post-bronchoscopy sputum; pauci-bacillary; pulmonary tuberculosis
- DOI
- 10.1080/07853890.2021.1908587
- URI
- https://oak.ulsan.ac.kr/handle/2021.oak/7920
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_pubmed_primary_33969770&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Diagnostic%20yield%20of%20post-bronchoscopy%20sputum%20for%20diagnosing%20pauci-bacillary%20pulmonary%20tuberculosis&offset=0&pcAvailability=true
- Publisher
- ANNALS OF MEDICINE
- Location
- 스웨덴
- Language
- 영어
- ISSN
- 0785-3890
- Citation Volume
- 53
- Citation Number
- 1
- Citation Start Page
- 576
- Citation End Page
- 580
-
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- Medicine > Medicine
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