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Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases

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Abstract
We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell-based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
Author(s)
강사윤권오윤김병조김선영김소연김수현김예슬김종국남태승배종숙백설희석진명손은희신경진신종화신현준오선영오승일이민영이상수이승한이혜정정우규조은빈조중양한석근허소영현재원홍윤호이혜림민주홍김병준김승우신하영오지영김우준김현진임영민김호진
Issued Date
2021
Type
Article
Keyword
Aquaporin-4adultmyelin oligodendrocyte glycoproteinprevalence
DOI
10.1177/1352458520948213
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7953
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2432856178&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Comparison%20of%20MOG%20and%20AQP4%20antibody%20seroprevalence%20in%20Korean%20adults%20with%20inflammatory%20demyelinating%20CNS%20diseases&offset=0&pcAvailability=true
Publisher
Multiple Sclerosis Journal
Location
영국
Language
한국어
ISSN
1352-4585
Citation Volume
27
Citation Number
6
Citation Start Page
964
Citation End Page
967
Appears in Collections:
Medicine > Medicine
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