Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases
- Abstract
- We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell-based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
- Issued Date
- 2021
- Type
- Article
- URI
- https://oak.ulsan.ac.kr/handle/2021.oak/7953
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2432856178&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Comparison%20of%20MOG%20and%20AQP4%20antibody%20seroprevalence%20in%20Korean%20adults%20with%20inflammatory%20demyelinating%20CNS%20diseases&offset=0&pcAvailability=true
- Publisher
- Multiple Sclerosis Journal
- Location
- 영국
- Language
- 한국어
- ISSN
- 1352-4585
- Citation Volume
- 27
- Citation Number
- 6
- Citation Start Page
- 964
- Citation End Page
- 967
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