KLI

Pregnancy outcomes in Korean women with ankylosing spondylitis

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Abstract
Background/Aims: Because ankylosing spondylitis (AS) mainly affects sacroiliac joints, special attention should be given to normal labour and pregnancy outcomes. Here, we investigate pregnancy outcomes in Korean women with AS.

Methods: Based on data from the Korean Health Insurance Review and Assessment Service claims database since July 2007, maternal complications were compared between women with AS and 1:10 matched general population by maternal age and year of delivery. Additionally, the 27 deliveries from 21 patients with AS who were seen at a tertiary hospital were retrospectively evaluated using 1: 4 matched control group by maternal and gestational age.

Results: In the population-based cohort, there were 1,293 deliveries in 996 patients with AS. Higher maternal age and more comorbidities were reported than in the general population. However, compared to age and delivery-year matched population, only the rate of Caesarean section (CS) was higher in women with AS (odds ratio, 1.52; 95% confidence interval, 1.36 to 1.70). Incidence of other maternal complications was comparable between women with AS and control subjects. In the hospital-based cohort, the CS rate was higher in women with AS (44.4% vs. 20.4%, p = 0.002). Causes of CS was not different in both groups, including previous uterine surgery. There were no significant differences in foetal outcomes, including growth restriction, foetal malformations and Apgar score.

Conclusions: CS deliveries were performed more often in women with AS. However, other maternal complications and offspring complications were similar between women with AS and healthy control subjects.
Author(s)
김예지김용길박은헤이승미이은봉이정선전종관
Issued Date
2021
Type
Article
Keyword
ankylosingCaesarean sectionPregnancySpondylitis
DOI
10.3904/kjim.2019.144
URI
https://oak.ulsan.ac.kr/handle/2021.oak/7956
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_kiss_primary_3882067&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Pregnancy%20outcomes%20in%20Korean%20women%20with%20ankylosing%20spondylitis&offset=0&pcAvailability=true
Publisher
KOREAN JOURNAL OF INTERNAL MEDICINE
Location
대한민국
Language
한국어
ISSN
1226-3303
Citation Volume
36
Citation Number
3
Citation Start Page
721
Citation End Page
721
Appears in Collections:
Medicine > Medicine
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