KLI

Mythical origins of the actin cytoskeleton

Metadata Downloads
Abstract
The origin of the eukaryotic cell is one of the greatest mysteries in modern biology. Eukaryotic-wide specific biological processes arose in the lost ancestors of eukaryotes. These distinctive features, such as the actin cytoskeleton, define what it is to be a eukaryote. Recent sequencing, characterization, and isolation of Asgard archaea have opened an intriguing window into the pre-eukaryotic cell. Firstly, sequencing of anaerobic sediments identified a group of uncultured organisms, Asgard archaea, which contain genes with homology to eukaryotic signature genes. Secondly, characterization of the products of these genes at the protein level demonstrated that Asgard archaea have related biological processes to eukaryotes. Finally, the isolation of an Asgard archaeon has produced a model organism in which the morphological consequences of the eukaryotic-like processes can be studied. Here, we consider the consequences for the Asgard actin cytoskeleton and for the evolution of a regulated actin system in the archaea-to-eukaryotic transition.
Author(s)
최한석Albert SchulteCaner AkilDavid LieblDuangkamon MuengsaenLinh T. TranRobert C. RobinsonWipa SugintaYoshihito Kitaoku
Issued Date
2021
Type
Article
Keyword
ActinActin cytoskeletonAnalysisAsgard archaeaCellsMedical collegesResearch institutes
DOI
10.1016/j.ceb.2020.08.011
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8020
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2451137784&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Mythical%20origins%20of%20the%20actin%20cytoskeleton&offset=0&pcAvailability=true
Publisher
CURRENT OPINION IN CELL BIOLOGY
Location
미국
Language
한국어
ISSN
0955-0674
Citation Volume
68
Citation Start Page
55
Citation End Page
63
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.