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Changes in Left Ventricular Ejection Fraction after Mitral Valve Repair for Primary Mitral Regurgitation

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Abstract
This study sought to identify the short- and long-term changes in left ventricular ejection fraction (LVEF) after mitral valve repair (MVr) in patients with chronic primary mitral regurgitation according to preoperative LVEF (pre-LVEF) and preoperative left ventricular end-systolic diameter (pre-LVESD). This study evaluated 461 patients. Restricted cubic spline regression models were constructed to demonstrate the long-term changes in postoperative LVEF (post-LVEF). The patients were divided into four groups according to pre-LVEF (<50%, 50-60%, 60-70%, and >= 70%). The higher the pre-LVEF was, the greater was the decrease in LVEF immediately after MVr. In the same pre-LVEF range, immediate post-LVEF was lower in patients with pre-LVESD >= 40 mm than in those with pre-LVESD < 40 mm. The patterns of long-term changes in post-LVEF differed according to pre-LVEF (p for interaction < 0.001). The long-term post-LVEF reached a plateau of approximately 60% when the pre-LVEF was >= 50%, but it seemed to show a downward trend after reaching a peak at approximately 3-4 years after MVr when the pre-LVEF was >= 70%. The patterns of short- and long-term changes in post-LVEF differed according to pre-LVEF and pre-LVESD values in patients with chronic primary mitral regurgitation after MVr.
Author(s)
김선옥남재식문영진배현준정경운정성호진지현최인철
Issued Date
2021
Type
Article
Keyword
Cardiovascular diseasechronic primary mitral regurgitationCoronary vesselsEjection fractionleft ventricular ejection fractionleft ventricular end-systolic diametermitral valve repairMortalityPatientsRegression analysisSurgery
DOI
10.3390/jcm10132830
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8034
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_ac899504b3b84a8bba8b1dbc05c634c3&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Changes%20in%20Left%20Ventricular%20Ejection%20Fraction%20after%20Mitral%20Valve%20Repair%20for%20Primary%20Mitral%20Regurgitation&amp;offset=0&amp;pcAvailability=true
Publisher
JOURNAL OF CLINICAL MEDICINE
Location
스위스
Language
영어
ISSN
2077-0383
Citation Volume
10
Citation Number
13
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
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