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Thiazolidinedione 최신지견

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Alternative Title
Recent Perspective on Thiazolidinedione
Abstract
Thiazolidinedione (TZD) is an insulin sensitizer that improves insulin resistance in the adipose tissue,
liver, and muscles and has a pancreas-protective effect while inhibiting gluconeogenesis. Its other
advantages include a glucose lowering effect, its durability, cardiovascular benefit, and recent evidence
in nonalcoholic fatty liver disease and dementia. However, there are also concerns about fluid retention/
edema/heart failure, bladder cancer, and fractures with TZD use. TZD can still be a useful option for
diabetes treatment when calculating risk versus benefit, but appropriate selection of patients is needed.
Author(s)
김원준
Issued Date
2021
Type
Article
Keyword
Diabetes mellitustype 2Hypoglycemic agentsPioglitazoneThiazolidinediones
DOI
10.4093/jkd.2021.22.2.97
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8059
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_kiss_primary_3892125&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Thiazolidinedione%20%EC%B5%9C%EC%8B%A0%EC%A7%80%EA%B2%AC&offset=0&pcAvailability=true
Publisher
당뇨병
Location
대한민국
Language
한국어
ISSN
1015-6461
Citation Volume
22
Citation Number
2
Citation Start Page
97
Citation End Page
104
Appears in Collections:
Medicine > Medicine
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