A randomised phase 2b study comparing the efficacy and safety of belotecan vs. topotecan as monotherapy for sensitive-relapsed small-cell lung cancer
- Abstract
- Background: This study compared the efficacy/safety of the camptothecin analogues belotecan and topotecan for sensitive-relapsed small-cell lung cancer (SCLC). Methods: One-hundred-and-sixty-four patients were randomised (1:1) to receive five consecutive daily intravenous infusions of topotecan (1.5 mg/m
- Issued Date
- 2021
- Type
- Article
- Keyword
- Aged; Camptothecin / adverse effects; Camptothecin / analogs & derivatives*; Camptothecin / therapeutic use; Female; Humans; Infusions; Intravenous; Lung Neoplasms / drug therapy*; Male; Middle Aged; Neoplasm Recurrence; Local / drug therapy*; Prognosis; Small Cell Lung Carcinoma / drug therapy*; Topoisomerase I Inhibitors / adverse effects; Topoisomerase I Inhibitors / therapeutic use; Topotecan / adverse effects; Topotecan / therapeutic use*
- URI
- https://oak.ulsan.ac.kr/handle/2021.oak/8145
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2461002438&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,A%20randomised%20phase%202b%20study%20comparing%20the%20efficacy%20and%20safety%20of%20belotecan%20vs.%20topotecan%20as%20monotherapy%20for%20sensitive-relapsed%20small-cell%20lung%20cancer&offset=0&pcAvailability=true
- Publisher
- BRITISH JOURNAL OF CANCER
- Location
- 영국
- Language
- 영어
- ISSN
- 0007-0920
- Citation Volume
- 124
- Citation Number
- 4
- Citation Start Page
- 713
- Citation End Page
- 720
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