KLI

High D-dimer is a predictor for short-term mortality in patients with active cancer and acute pulmonary embolism

Metadata Downloads
Abstract
Objectives: Acute pulmonary embolism (PE) is the main cause of death in cancer patients, but there are limited prognostic tools for the patients with active cancer and acute PE. We aimed to identify prognostic factors of 30-day mortality in patients with active cancer and acute PE.

Methods: This retrospective observational study included all adult patients aged >= 18 years with active cancer and acute PE from February 2017 to February 2019 at the emergency department in tertiary care hospital, Seoul, Korea. The primary outcome is 30-day mortality.

Results: A total of 178 patients were included with a mean age of 63.9 years (SD 10.4) and males of 52.8%. The overall 30-day mortality rate was 30.9%. In a multivariable logistic analysis, high D-dimer, defined as >= median value of 14.7 mu g/mL, with odds ratio (OR) 2.47 (95% confidence interval [CI], 1.15-5.33), high Pulmonary Embolism Severity Index (PESI) scores with OR 2.95 (95% CI, 1.21-7.75) for class IV and OR 2.90 (95% CI, 1.06-7.90) for class V, and Eastern Cooperative Oncology Group (ECOG) performance status 3/4 with OR 3.22 (95% CI, 1.18-8.76) were independent predictors of 30-day mortality.

Conclusion: High D-dimer values, high PESI scores, and poor ECOG performance status may be reliable predictors of mortality in patients with active cancer and acute PE.
Author(s)
허은주권효정채보라김윤정이윤선
Issued Date
2021
Type
Article
Keyword
CancerD-dimerMortalityPrognosisPulmonary embolism
DOI
10.22514/sv.2021.083
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8296
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_crossref_primary_10_22514_sv_2021_083&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,High%20D-dimer%20is%20a%20predictor%20for%20short-term%20mortality%20in%20patients%20with%20active%20cancer%20and%20acute%20pulmonary%20embolism&offset=0&pcAvailability=true
Publisher
SIGNA VITAE
Location
싱가포르
Language
영어
ISSN
1334-5605
Citation Volume
17
Citation Number
5
Citation Start Page
58
Citation End Page
63
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.