KLI

Retrograde transvenous obliteration for the prevention of variceal rebleeding in patients with hepatocellular carcinoma: a multicentre retrospective study

Metadata Downloads
Abstract
AIM: To evaluate the effectiveness and safety of retrograde transvenous obliteration (RTO)
for the prevention of variceal rebleeding variceal rebleeding in patients with hepatocellular
carcinoma (HCC).
MATERIALS AND METHODS: This multicentre retrospective study enrolled 79 patients with
HCC who underwent RTO for the prevention of variceal rebleeding. Successful occlusion of the
gastrorenal shunt and obliteration of the gastric varices were achieved in 74 patients, with a
technical success rate of 93.7%. Of the remaining 74 patients (mean age, 64.910.3 years; 56
men), 66 (90.4%) had gastroesophageal varices and seven (9.6%) had isolated gastric varices.
Thirty-two patients (43.8%) underwent balloon-occluded RTO, 40 patients (54.8%) underwent
plug-assisted RTO, and one patient (1.4%) underwent coil-assisted RTO. No patients had major
procedural complications.
RESULTS: Rebleeding occurred in seven patients (9.6%) during the follow-up period. The 6-
week and 1-year actuarial probabilities of patients remaining free of rebleeding were
90.83.6% and 88.64.1%, respectively. The median survival was 12.6 (95% confidence interval
[CI] 8e17.3) months. The 6-week, 1-year, and 3-year actuarial probabilities of survival were
83.24.4%, 51.16.6%, and 32.77%, respectively. New or worsening ascites and oesophageal
varices occurred in 12 (16.4%) and 13 patients (17.8%), respectively, during the follow-up
period. Overt hepatic encephalopathy occurred in one patient (1.4%) during the follow-up
period. The ChildePugh score remained comparable to that at baseline at 1 and 3 months.
CONCLUSION: RTO was effective and safe in preventing variceal rebleeding in patients with
HCC.
Author(s)
권동일김영환노승연신지훈이재명전웅배한기창J. Tsauo
Issued Date
2021
Type
Article
Keyword
Care and treatmentHepatomaMedical researchMedicineExperimentalPrevention
DOI
10.1016/j.crad.2021.05.011
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8315
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2543452877&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Retrograde%20transvenous%20obliteration%20for%20the%20prevention%20of%20variceal%20rebleeding%20in%20patients%20with%20hepatocellular%20carcinoma:%20a%20multicentre%20retrospective%20study&offset=0
Publisher
CLINICAL RADIOLOGY
Location
영국
Language
영어
ISSN
0009-9260
Citation Volume
76
Citation Number
9
Citation Start Page
681
Citation End Page
687
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.