KLI

Ultrasound Echogenicity of Papillary Thyroid Cancer Is Affected by Tumor Growth Patterns and Tumor Fibrosis

Metadata Downloads
Abstract
Background/aim: The association between preoperative ultrasound (US) echogenicity and histopathological characteristics of papillary thyroid cancer (PTC) has been rarely investigated is not well characterized. This study evaluated a relationship between the clinical characteristics of PTC, histopathological phenomena including tumor growth patterns (TGPs) and tumor fibrosis (TF), and US echogenicity.

Patients and methods: In total, 170 patients with PTC (<2 cm) underwent total thyroidectomy with central neck dissection. Demographics, US echogenicity, tumor size, extra-thyroidal extension (ETE), lymph node metastasis (LNM) within the central and lateral neck, TGPs, and TF percentage were reviewed.

Results: Patients with TGP II (encapsulated growth with partial pericapsular extension) and III (infiltrative growth) were more frequently burdened by ETE and lateral neck LNM compared to patients with TGP I (encapsulated growth with a well-defined cystic or solid characteristic). Older age was significantly deterministic of TGP III, and male gender and higher TF percentage were independent risk factors for lateral neck LNM. TGP III and TF were independent determining factors for marked hypoechogenicity on US.

Conclusion: PTC with TGP II and III and higher tumor fibrosis exhibited more aggressive clinicopathologic behaviors. TGP III and TF were determinants for marked hypoechogenicity.
Author(s)
김상수김인주손석만신동훈이병주이윤세이진춘임윤성
Issued Date
2021
Type
Article
Keyword
Papillary thyroid cancermetastasistumor fibrosistumor growth patternultrasonography.
DOI
10.21873/invivo.12421
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8374
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2519812801&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,Ultrasound%20Echogenicity%20of%20Papillary%20Thyroid%20Cancer%20Is%20Affected%20by%20Tumor%20Growth%20Patterns%20and%20Tumor%20Fibrosis&amp;offset=0
Publisher
IN VIVO
Location
그리스
Language
한국어
ISSN
0258-851X
Citation Volume
35
Citation Number
3
Citation Start Page
1633
Citation End Page
1640
Appears in Collections:
Medicine > Medicine
Authorize & License
  • Authorize공개
Files in This Item:
  • There are no files associated with this item.

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.