KLI

Incidence and Treatment Outcome of Rhinosinusitis before Kidney Transplantation: A Retrospective Cohort Study

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Abstract
Background: The use of immunosuppressants after transplantation can aggravate sinus infections. Although kidney transplantation (KT) recipients are administered strong immunosuppressant therapy, there is few consensus or reports on incidence and treatment of rhinosinusitis before KT. This study was undertaken to analyze the results of a cohort of KT recipients that underwent sinonasal evaluation before KT. Methods: Observational retrospective cohort data were analyzed from adults who underwent a KT between January 2015 and December 2018. In total, 966 patients were screened by clinical history, nasal endoscopy, and plain X-ray before KT. Results: A total of 86 patients (8.9%) were diagnosed with rhinosinusitis. Twenty-three of the eighty-six patients (26.7%) who underwent plain X-ray on second follow up were successfully treated with primary and secondary antibiotics, saline irrigation, and INS. From the remaining 63 patients who underwent additional CT on second follow up, 43 patients were treated with primary or secondary antibiotics and 20 patients (10 with chronic rhinosinusitis and 10 with fungal ball) were treated with endoscopic sinus surgery. There were no serious complications affecting patient mortality after KT. Conclusion: We report that 8.9% of patients showed abnormal findings in sinonasal evaluation before KT. Although most patients did not require surgery, surgery is recommended for active rhinosinusitis, which does not respond to medication, and for fungal rhinosinusitis to prevent postoperative sinonasal infection.
Author(s)
김민수김성희김지희오진석
Issued Date
2021
Type
Article
Keyword
Antibioticscomputed tomographyEdemaEndoscopyFungal infectionsimagingimmunodeficiencyImmunosuppressive agentsKidney transplantationKidneysMedical imagingMortalityPatientsRhinosinusitissinusitisSurgeryTransplants & implants
DOI
10.3390/jpm11060553
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8516
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_478f5049af1a497685c2f5d16f45858a&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Incidence%20and%20Treatment%20Outcome%20of%20Rhinosinusitis%20before%20Kidney%20Transplantation:%20A%20Retrospective%20Cohort%20Study&offset=0&pcAvailability=true
Publisher
JOURNAL OF PERSONALIZED MEDICINE
Location
스위스
Language
영어
ISSN
2075-4426
Citation Volume
11
Citation Number
6
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
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