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Outflow vein venoplasty of left lateral section graft for living donor liver transplantation in infant recipients

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Abstract
The orifice size of the LHV trunk in LLS grafts is often too small for direct anastomosis. Several methods were developed to enlarge the graft and recipient hepatic vein orifices. This study described our surgical techniques to secure hepatic vein reconstruction in infant recipients and analyzed the patency outcomes. Twelve infants undergoing pediatric LDLT were selected during 2-year study period between January 2018 and December 2019. Surgical techniques and vascular complications of graft hepatic vein outflow were analyzed. The mean recipient age was 12.5 +/- 4.5 months; mean body weight was 9.4 +/- 1.0 Kg; and mean graft-recipient weight ratio was 2.8 +/- 0.6%. Primary diseases were biliary atresia in six patients, metabolic diseases in two, hepatoblastoma in two, and acute liver failure in two. Eight LLS grafts were recovered through an open method, and four LLS grafts were recovered through a laparoscopic method. A small superficial LHV branch was present in five of 12 LLS grafts, which was opened to widen the graft hepatic vein orifice. Incision-and-patch venoplasty was performed in 10, unification venoplasty in 1 and no venoplasty in 1. All four LLS grafts recovered through a laparoscopic approach required circumferential vein patch because of very short hepatic vein stump. No patient experienced graft hepatic vein-associated vascular complications during the follow-up period of 19.3 +/- 9.3 months. Our surgical techniques with incision-and-patch venoplasty for LLS grafts is beneficial to reduce the risk of hepatic vein outflow obstruction in recipients receiving LLS grafts.
Author(s)
권용재권현희김경모김기훈남궁정만박길춘안철수오석희황신
Issued Date
2021
Type
Article
Keyword
AnalysisBody weightDonation of organstissuesetcFemaleFollow-Up StudiesGraft OcclusionVascular - etiologyGraft OcclusionVascular - prevention & controlHepatic Veins - surgeryHumansInfantleft hepatic veinLiverLiver Transplantation - methodsLiving DonorsMalepediatric transplantationProspective StudiesRetrospective StudiesstenosisTransplantationTreatment Outcomeunification venoplasty Vascular Grafting - methods
DOI
10.1111/petr.13970
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8548
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_proquest_miscellaneous_2477263387&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Outflow%20vein%20venoplasty%20of%20left%20lateral%20section%20graft%20for%20living%20donor%20liver%20transplantation%20in%20infant%20recipients&offset=0&pcAvailability=true
Publisher
PEDIATRIC TRANSPLANTATION
Location
미국
Language
한국어
ISSN
1397-3142
Citation Volume
25
Citation Number
5
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
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