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The Efficacy and Safety of Dual-Frequency Ultrasound for Improving Skin Hydration and Erythema in Patients with Rosacea and Acne

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Abstract
Inflammatory skin diseases, such as rosacea and acne, are major causes of facial erythema and accompanying skin barrier dysfunction. Several methods to restore the impaired skin barrier and improve facial erythema, such as medication, radiofrequency, laser, and ultrasound therapy were attempted. This study evaluated the efficacy and safety of dual-frequency ultrasound with impulse mode, for improving skin hydration and erythema in Asian subjects with rosacea and acne. Twenty-six subjects with facial erythema received an ultrasound treatment once per week, for 4 weeks, over both cheeks. The erythema index and transepidermal water loss (TEWL) were measured at each visit. Clinicians assessed the erythema improvement and patients evaluated their satisfaction level. The average decrease in TEWL and erythema index at 6 weeks was 5.37 +/- 13.22 g center dot h(-1)center dot m(-2) (p = 0.020) and 39.73 +/- 44.21 (p = 0.010), respectively. The clinician's erythema assessment and the subject satisfaction questionnaire score significantly improved at final follow-up (p < 0.001; p = 0.003, respectively). No serious adverse effects were observed during the treatment and follow-up periods. The dual-frequency ultrasound with impulse mode appears to be effective and safe for improving skin hydration and erythema in patients with rosacea and acne.
Author(s)
김영재문익준원종현이미우이우진이해웅장성은최지호
Issued Date
2021
Type
Article
Keyword
acnefacial erythemainflammationrosaceaskinultrasound
DOI
10.3390/jcm10040834
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8744
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_d7a12d0fcb734a18b6eefaa4a5a9fb77&amp;context=PC&amp;vid=ULSAN&amp;lang=ko_KR&amp;search_scope=default_scope&amp;adaptor=primo_central_multiple_fe&amp;tab=default_tab&amp;query=any,contains,The%20Efficacy%20and%20Safety%20of%20Dual-Frequency%20Ultrasound%20for%20Improving%20Skin%20Hydration%20and%20Erythema%20in%20Patients%20with%20Rosacea%20and%20Acne&amp;offset=0&amp;pcAvailability=true
Publisher
Journal of clinical medicine
Location
스위스
Language
영어
ISSN
2077-0383
Citation Volume
10
Citation Number
4
Citation Start Page
834
Citation End Page
834
Appears in Collections:
Medicine > Medicine
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