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Evaluation of skin cancer resection guide using hyper-realistic in-vitro phantom fabricated by 3D printing

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Abstract
Skin cancer usually occurs in the facial area relatively exposed to sunlight. Medical imaging can confirm the invasiveness and metastasis of skin cancer, which is used to establish a surgical plan. However, there is no method of directly marking this information on the patient's skin in the operating room. We evaluated a skin cancer resection guide that marks resection areas including safety margins on the patient's skin based on medical images and in-vitro phantom fabricated via 3D printing. The in-vitro phantom, which includes the skull, skin, and five different cancer locations was designed and fabricated based on a CT image of a patient. Skin cancer resection guides were designed using a CT image of an in-vitro phantom, with a safety margin, and four injection points at each cancer. The guide was used to insert 16 cc intravenous catheters into each cancer of the phantom, which was rescanned by CT. The catheter insertion point and angle were evaluated. The accuracy of the insertion points was 2.09 +/- 1.06 mm and cosine similarities was 0.980 +/- 0.020. In conclusion, skin cancer resection guides were fabricated to mark surgical plans on the patient's skin in the operating room. They demonstrated reasonable accuracies in actual clinical settings.
Author(s)
옥준혁김태훈이상욱양태성김민지정우식최종우김남국
Issued Date
2021
Type
Article
Keyword
3-D printersBiomarkersCathetersComputed tomographyIntravenous administrationInvasivenessMetastasesPatientsSkin cancer
DOI
10.1038/s41598-021-88287-4
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8747
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_doaj_primary_oai_doaj_org_article_91144e322c224ad8ad0c5106d100b215&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Evaluation%20of%20skin%20cancer%20resection%20guide%20using%20hyper-realistic%20in-vitro%20phantom%20fabricated%20by%203D%20printing&offset=0&pcAvailability=true
Publisher
SCIENTIFIC REPORTS
Location
영국
Language
영어
ISSN
2045-2322
Citation Volume
11
Citation Number
1
Citation Start Page
0
Citation End Page
0
Appears in Collections:
Medicine > Medicine
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