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Glutathione modified N-doped carbon dots for sensitive and selective dopamine detection

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Abstract
The water-soluble N-doped carbon dots (NCDs) are designed by simple hydrothermal treatment of aqueous mixture of citric acid and urea. The initially prepared NCDs are further been passivated by L-glutathione (GSH) through carbodiimide-activated coupling reaction to enhance the emissive properties of the NCDs. The asobtained passivated carbon dots (GSH-NCDs) show intense blue emission at 440 nm when excited at 355 nm. However, this emission is observed to be quenched selectively in the presence of dopamine (DA) leading to design a platform for DA detection. The quenching of fluorescence of GSH-NCDs is dependent on DA concentration. The limit of detection is 1.01 nM, with a linear detection ranges from 20 nM to 10 μM (R2 = 0.992). The average lifetime values and the spectral profile of GSH-NCDs in absence and presence of DA indicate the possibility of photoinduced electron transfer assisted inner filter effect mechanism for the DA induced quenching of GSH-NCDs’ fluorescence. Further experiments show that the as-designed DA detection technique works successfully for biological fluids.
Author(s)
왕림림정진석허승현Jayasmita Jana
Issued Date
2021
Type
Article
Keyword
AnalysisCarbon dotsCardiac glycosidesCardiotonic agentsCitric acidDopamine sensorFluorescenceFluorescentGlutathionePhenolsSelectivitySensitivitySensorsThiolsUrea
DOI
10.1016/j.dyepig.2020.109028
URI
https://oak.ulsan.ac.kr/handle/2021.oak/8954
https://ulsan-primo.hosted.exlibrisgroup.com/primo-explore/fulldisplay?docid=TN_cdi_gale_infotracacademiconefile_A648921461&context=PC&vid=ULSAN&lang=ko_KR&search_scope=default_scope&adaptor=primo_central_multiple_fe&tab=default_tab&query=any,contains,Glutathione%20modified%20N-doped%20carbon%20dots%20for%20sensitive%20and%20selective%20dopamine%20detection&offset=0&pcAvailability=true
Publisher
DYES AND PIGMENTS
Location
영국
Language
영어
ISSN
0143-7208
Citation Volume
186
Citation Number
1
Citation Start Page
109028
Citation End Page
109028
Appears in Collections:
Engineering > Material Engineering
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