Visible-Light Photoredox-Catalyzed α-Allylation of α-Bromocarbonyl Compounds Using Allyltrimethylsilane

Abstract

The development of a greener allylation reagent for α?allylation of carbonyl compounds is of great necessity. Here we present allyltrimethylsilane as a novel allylation reagent in the photoredox?catalyzed α?allylation of carbonyl compounds such as ketones, esters, and amides. The reaction process shows good functional group tolerance and generates a good yield of the product. The reaction mechanism is a radical?mediated reaction by photo?induced single electron transfer.